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The chemical and hydroxyl radical scavenging activity changes of ginsenoside-Rb1 by heat processing
- Authors
- Lee, Y.J.; Kim, H.Y.; Kang, K.S.; Lee, J.G.; Yokozawa, T.; Park, J.H.
- Issue Date
- 2008
- Keywords
- Ginsenoside Rb1; Glycine; Hydroxyl radical; Maillard reaction
- Citation
- Bioorganic and Medicinal Chemistry Letters, v.18, no.16, pp 4515 - 4520
- Pages
- 6
- Indexed
- SCOPUS
- Journal Title
- Bioorganic and Medicinal Chemistry Letters
- Volume
- 18
- Number
- 16
- Start Page
- 4515
- End Page
- 4520
- ISSN
- 0960-894X
1464-3405
- Abstract
- The chemical and hydroxyl radical ({radical dot}OH) scavenging activity changes of ginsenoside Rb1 (Rb1) by heat processing were investigated in this study. Rb1 was changed into 20(S)-Rg3, 20(R)-Rg3, Rk1, and Rg5 by heat processing through glucosyl elimination and epimerization of carbon-20 by SN1 reaction. The glucosyl moiety, separated from Rb1, made Maillard reaction product (MRPs) with glycine. The generations of 20(S)-Rg3 and MRPs were related to the increased {radical dot}OH scavenging activity of Rb1 by heat processing. ? 2008 Elsevier Ltd. All rights reserved.
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