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Characterization of KRC-108 as a TrkA Kinase Inhibitor with Anti-Tumor Effects

Lee, Hyo Jeong; Moon, Yeongyu; Choi, Jungil; Heo, Jeong Doo; Kim, Sekwang; Nallapaneni, Hari Krishna; Chin, Young-Won; Lee, Jongkook; Han, Sun-Young

ArticleIssue Date2022CitationBiomolecules & Therapeutics, v.30, no.4, pp 360 - 367Publisher한국응용약물학회
SCISCIESCOPUS
Design and synthesis of 3-(4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)-1H-quinolin-2-ones as VEGFR-2 kinase inhibitors

Han, Sun-Young; Choi, Jie Won; Yang, Jeon; Chae, Chong Hack; Lee, Jongkook; Jung, Heejung; Lee, Kwangho; Ha, Jae Du; Kim, Hyoung Rae; Cho, Sung Yun

ArticleIssue Date2012CitationBioorganic & Medicinal Chemistry Letters, v.22, no.8, pp 2837 - 2842PublisherPergamon Press Ltd.
SCISCIESCOPUS
Design and synthesis of triazolopyridazines substituted with methylisoquinolinone as selective c-Met kinase inhibitors

Ryu, Jae Wook; Han, Sun-Young; Yun, Jeong In; Choi, Sang-Un; Jung, Heejung; Du Ha, Jae; Cho, Sung Yun; Lee, Chong Ock; Kang, Nam Sook; Koh, Jong Sung, et al.

ArticleIssue Date2011CitationBioorganic & Medicinal Chemistry Letters, v.21, no.23, pp 7185 - 7188PublisherPergamon Press Ltd.
SCISCIESCOPUS
Discovery of a potent small molecule SIRT1/2 inhibitor with anticancer effects

Choi, Gildon; Lee, Jongkook; Jeong, Yeon ji; Woo, Jimin; Kang, Nam Sook; Cho, Sung Yun; Kim, Hyoung Rae; Ha, Jab Du; Han, Sun-Young

ArticleIssue Date2013CitationInternational Journal of Oncology, v.43, no.4, pp 1205 - 1211PublisherDemetrios A. Spandidos Ed. & Pub.
SCISCIESCOPUS
Discovery of quinolinone derivatives as potent FLT3 inhibitors

Chung, Hye Jin; Kamli, Majid Rasool; Lee, Hyo Jeong; Ha, Jae Du; Cho, Sung Yun; Lee, Jongkook; Kong, Jae Yang; Han, Sun-Young

ArticleIssue Date2014CitationBiochemical and Biophysical Research Communications, v.445, no.3, pp 561 - 565PublisherAcademic Press
SCISCIESCOPUS
Effects of KRC-108 on the Aurora A activity and growth of colorectal cancer cells

Chung, Hye Jin; Park, Kyeong Ryang; Lee, Hyo Jeong; Lee, Jongkook; Kim, Jeong-Hyun; Kim, Yong-Chul; Han, Sun-Young

ArticleIssue Date2015CitationBiochemical and Biophysical Research Communications, v.461, no.4, pp 605 - 611PublisherAcademic Press
SCISCIESCOPUS
Evaluation of a multi-kinase inhibitor KRC-108 as an anti-tumor agent in vitro and in vivo

Han, Sun-Young; Lee, Chong Ock; Ahn, Sung-Hoon; Lee, Mi-Ok; Kang, So-Young; Cha, Hyuk-Jin; Cho, Sung Yun; Ha, Jae Du; Ryu, Jae Wook; Jung, Heejung, et al.

ArticleIssue Date2012CitationInvestigational New Drugs, v.30, no.2, pp 518 - 523PublisherKluwer Academic Publishers
SCIESCOPUS
FMS-like tyrosine kinase 3 inhibitors: a patent review

Lee, Jongkook; Paek, Seung-Mann; Han, Sun-Young

ArticleIssue Date2011CitationExpert Opinion on Therapeutic Patents, v.21, no.4, pp 483 - 503PublisherAshley Publications Ltd.
SCIESCOPUS
Resistance to the c-Met inhibitor KRC-108 induces the epithelial transition of gastric cancer cells

Kim, Dong Chul; Park, Kyeong Ryang; Jeong, Yeon Ji; Yoon, Hyonok; Ahn, Mi Jeong; Rho, Gyu-Jin; Lee, Jongkook; Gong, Young-Dae; Han, Sun-Young

ArticleIssue Date2016CitationOncology Letters, v.11, no.2, pp 991 - 997PublisherSpandidos Publications
SCISCIESCOPUS
Synthesis and structure-activity relationship of aminopyridines with substituted benzoxazoles as c-Met kinase inhibitors

Lee, Jongkook; Han, Sun-Young; Jung, Heejung; Yang, Jeon; Choi, Jie-Won; Chae, Chong Hack; Park, Chi Hoon; Choi, Sang Un; Lee, Kwangho; Du Ha, Jae, et al.

ArticleIssue Date2012CitationBioorganic & Medicinal Chemistry Letters, v.22, no.12, pp 4044 - 4048PublisherPergamon Press Ltd.
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