Scientific considerations for the biosafety of the off-target effects of gene editing in cropsopen access
- Lee, S.-W.; Kim, Y.-H.
- Issue Date
- Korean Society of Plant Biotechnology
- Gene-edited crop; Gene-editing; Genetically modified crop; Off-target effects; Safety
- Journal of Plant Biotechnology, v.47, no.3, pp.185 - 193
- Journal Title
- Journal of Plant Biotechnology
- Start Page
- End Page
- The number of commercially approved gene-edited crops is gradually increasing, and in South Korea, it has led to intense investment in gene-edited crop development to increase international competitiveness. However, as with genetically modified crops, the safety of gene-edited crops regarding unexpected risks for humans and the environment is subject to an ongoing debate. In particular, unintentional “off-target effects” have become the center of controversy. In this review, we discuss typical plant characteristics (including somatic variation and ploidy), the extent of various off-target effects in genetically modified crops generated via horizontal transfer in nature, and the off-target effects in commercial genetically modified crops. We conclude that most off-target effects possibly occurring in gene-edited crops are not expected to be critically harmful to humans or the environment. Therefore, existing regulation for genetically modified crops should be enough for the risk assessment of gene-edited crops. ? Korean Society for Plant Biotechnology.
- Files in This Item
- There are no files associated with this item.
- Appears in
- 사범대학 > 생물교육과 > Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.