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Phenolics of Propolis and in vitro Protective Effects against Oxidative Stress Induced CytotoxicityPhenolics of Propolis and in vitro Protective Effects against Oxidative Stress Induced Cytotoxicity
- Other Titles
- Phenolics of Propolis and in vitro Protective Effects against Oxidative Stress Induced Cytotoxicity
- Issue Date
- Jun-2012
- Publisher
- 농업생명과학연구원
- Keywords
- Propolis; Phenolics; Antioxidant activity; Neuronal cell protection; Propolis; Phenolics; Antioxidant activity; Neuronal cell protection
- Citation
- 농업생명과학연구, v.46, no.3, pp 87 - 95
- Pages
- 9
- Indexed
- KCI
- Journal Title
- 농업생명과학연구
- Volume
- 46
- Number
- 3
- Start Page
- 87
- End Page
- 95
- ISSN
- 1598-5504
2383-8272
- Abstract
- Anti-neurodegenerative activities of aqueous extract from propolis were investigated. The aqueous extracts showed strong antioxidant activities in malondialdehyde (MDA) assay, and it effectively inhibited lipid peroxidation. In addition, the aqueous extract presented protective effects against H2O2-induced neurotoxicity in a dose-dependent manner. Our study verified that the aqueous extract has strong antioxidant activity and neuronal cell protective effect which is correlated with its total phenolics (290.75 mg GAE/g) including p-coumaric acid, vanillic acid and gallic acid. These phenolics of propolis may reduce the risk of neurodegenerative disorders, and can be utilized as effective and safe resources of functional food.
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