Detailed Information
Cited 0 time in 
Cited 1 time in 
Cited 1 time in
Metadata Downloads
Anti-inflammatory effect of Eucommia ulmoides Oliver bark extract on p.Gingivalis LPS-induced YD-38 cells
- Authors
- Kim, Y.-J.; Heo, W.; Choi, H.-S.; Kang, K.S.; Hwang, G.S.; Baek, J.Y.; Koo, B.A.; Kim, H.Y.
- Issue Date
- 2019
- Publisher
- 한국생약학회
- Keywords
- Anti-inflammation; Eucommia ulmoides oliv. bark (EU); Periodontitis; Porphyromonas gingivalis-lps (LPS-PG); YD-38 cells
- Citation
- 생약학회지, v.50, no.3, pp 185 - 190
- Pages
- 6
- Indexed
- SCOPUS
KCI
- Journal Title
- 생약학회지
- Volume
- 50
- Number
- 3
- Start Page
- 185
- End Page
- 190
- ISSN
- 0253-3073
- Abstract
- Periodontitis is a chronic inflammatory disease and gums pull away from the teeth and form spaces. The main goal of treatment is to control the infection and anti-inflammation. Eucommia ulmoides Oliv. Bark (EU) is a traditional Korean herbal used for the treatment of arthritis and hypertension. In the present study, we investigated the anti-inflammatory properties of EU in Porphyromonas gingivalis-LPS (LPS-PG) induced YD-38 epithelial cells. We observed significant inhibition of nitric oxide (NO) production and the expression of interleukin-8 (IL-8), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), cyclooxygenase-2 (COX-2) in LPS-PG-induced YD-38 cells. These results support that EU has an anti-inflammatory effects for the treatment of periodontitis. ? 2019, Korean Society of Pharmacognosy. All rights reserved.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 자연과학대학 > 식품영양학과 > Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.