Structure Determination of Four Compounds Isolating from Rhizomes of Rhodiola rosea using NMR Spectrometer

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초록

Rhodiola rosea, also known as gold root or rose root, is a perennial plant in the family of Crassulaceae. The rhizhome of R. rosea has been widely used as a hemostatic, tonic for burns and contusions in traditional Chinese medicine. Recent studies reported its strong antioxidant and adaptogenic properties. In this paper, we attempted to isolate compounds from the methanolic extract of R. rosea rhizomes. Four compounds including one new compound (1), two kaempferol glycosides (3 and 4) were isolated from chloroform and ethyl acetate soluble fraction of R. rosea extract. The structures of 1 similar to 4 including relative stereochemistry were determined by MS and NMR analysis.

키워드

Rhodiola rosea; constituents; flavonoid; 1D and 2D NMR; LOW-DOSE REGIMEN; DOUBLE-BLIND; EXTRACT; STRESS; SHR-5; CONSTITUENTS; PERFORMANCE; PLACEBO; FATIGUE; L.
제목
Structure Determination of Four Compounds Isolating from Rhizomes of Rhodiola rosea using NMR Spectrometer
저자
Kim, Yun Na; Lee, Jae Sun; Kim, Chul Ho; Jeong, Eun Ju
DOI
10.6564/JKMRS.2017.21.4.145
발행일
2017-12
유형
Article
저널명
Journal of the Korean Magnetic Resonance Society
권
21
호
4
페이지
145 ~ 151