An optimized extraction technique for acetylcholinesterase inhibitors from the Camellia japonica seed cake by using response surface methodology

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6
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6

초록

The response surface methodology (RSM) was used to optimize the extraction conditions for the acetylcholinesterase (AchE) inhibitory activity and extraction yield from Camellia japonica seed cake. Predicted values for AchE inhibition and extraction yield were 19.41 and 13.35%, respectively, which are in good agreement with the experimental values from validation, suggesting that RSM may provide a useful tool to optimization processes.

키워드

Camellia japonica; camellia seed cake; acetylcholinesterase; Alzheimer's disease; response surface methodology; ALZHEIMER-DISEASE; OIL; PHYTOCHEMICALS; IMPAIRMENT; FLAVONOIDS; OLEIFERA; RISK; MICE
제목
An optimized extraction technique for acetylcholinesterase inhibitors from the Camellia japonica seed cake by using response surface methodology
저자
Kim, Jae Kyeom; Kim, Cho Rong; Lim, Ho-Jeong; Nam, Sang Hae; Joo, Ok Soo; Shin, Dong-Hoon; Shin, Eui-Cheol
DOI
10.1080/09168451.2014.915723
발행일
2014-07
유형
Article
저널명
Bioscience, Biotechnology and Biochemistry
권
78
호
7
페이지
1237 ~ 1241