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과산화수소(H2O2)로 유도된 산화 스트레스에 대한 뉴그린 추출물의 신경세포 보호효과 및 생리활성물질 분석
- Ha, J.S.;
- Park, S.K.;
- Park, C.H.;
- Seung, T.W.;
- Guo, T.J.;
- ... Heo, H.J.;
- 외 4명
SCOPUS
8초록
In vitro antioxidant activities and neuronal cell protective effects of the ethyl acetate fraction of a new green extract (Brassica oleracea var. botytis aut italiana) against H2O2-induced oxidative stress were investigated, and its industrial feasibility was evaluated. The extract showed the highest contents of total phenolic compounds among other extracts as well as a 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) diammonium salt (ABTS) radical scavenging activity and malondialdehyde (MDA) inhibitory effect. This extract not only decreased the intracellular reactive oxygen (ROS) level but also protected the neuronal cells against H2O2-induced oxidative stress. On analysis using gas chromatograph-mass spectrometry, the following phenolic compounds were identified: quinic acid, ferulic acid, and caffeic acid. Collectively, these results suggest that this new green extract could contain functional substances that would help prevent the risk of neurodegenerative disease.
키워드
- 제목
- 과산화수소(H2O2)로 유도된 산화 스트레스에 대한 뉴그린 추출물의 신경세포 보호효과 및 생리활성물질 분석
- 제목 (타언어)
- Neuronal cell protective effect of new green extract against H2O2-induced oxidative stress and analysis of bioactive compounds
- 저자
- Ha, J.S.; Park, S.K.; Park, C.H.; Seung, T.W.; Guo, T.J.; Kang, J.Y.; Lee, D.S.; Kim, J.M.; Lee, U.; Heo, H.J.
- 발행일
- 2015-10
- 유형
- Article
- 저널명
- 한국식품과학회지
- 권
- 47
- 호
- 5
- 페이지
- 673 ~ 679