The Glasgow Prognostic Score is a significant predictor of peripheral T-cell lymphoma (PTCL) treated with CHOP-based chemotherapy and comparable with PTCL prognostic scores
- Huh, SeokJae; Oh, Sung Yong; Lee, Suee; Lee, Ji Hyun; Kim, Sung Hyun; Lee, Gyeong-Won; Kim, Seok Jin; Kim, Won Seog; Lee, Ho Sup; Jo, Jae-Cheol; Kim, Moon Jin; Kwon, Jung Hye; Kim, Hyo-Jin
- Issue Date
- SPRINGER JAPAN KK
- Peripheral T-cell lymphoma; Glasgow Prognostic Score; Prognostic scores
- INTERNATIONAL JOURNAL OF HEMATOLOGY, v.110, no.4, pp.438 - 446
- Journal Title
- INTERNATIONAL JOURNAL OF HEMATOLOGY
- Start Page
- End Page
- The Glasgow Prognostic Score (GPS) serves a prognostic role in several lymphomas. The objectives of the present study were to determine whether GPS predicts clinical outcomes and to compare the utility of four prognostic scores, including GPS, in patients diagnosed with peripheral T-cell lymphoma (PTCL). We selected for this retrospective study 96 patients consecutively diagnosed with PTCL according to the World Health Organization classification from January 2002 to February 2013 and followed up in five different institutions. Low GPS was a good prognostic biomarker of progression-free survival (PFS, P = 0.030) and overall survival (OS, P = 0.013). Estimated 3-year OS rates (low-risk vs. intermediate- or high-risk) by the International Prognostic Index (IPI), the Prognostic Index for T-cell lymphoma (PIT), the International Peripheral T-cell Lymphoma Project (IPTCLP) score, and GPS were 83% vs. 44% (P < 0.001), 68% vs. 37% (P = 0.004), 71% vs. 26% (P < 0.001) and 68% vs. 51% (P = 0.031), respectively. These results indicate that GPS has prognostic value for PTCL. In addition, all four prognostic scores demonstrate their usefulness in assessing PTCL outcomes.
- Files in This Item
- There are no files associated with this item.
- Appears in
- College of Medicine > Department of Medicine > Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.