Correction to: Transglutaminase-2 regulates Wnt and FoxO3a signaling to determine the severity of osteoarthritis (Scientific Reports, (2020), 10, 1, (13228), 10.1038/s41598-020-70115-w)

Abstract

Correction to: Scientific Reportshttps://doi.org/10.1038/s41598-020-70115-w, published online 06 August 2020. The original version of this Article contained errors. Due to errors during figure assembly, in Fig. 2b, a Sham (8wks) ZDON/MMP-3 image was a duplication of a Sham (8wks) Vehicle/MMP-3 image. The figure was replaced to include a correct Sham (8wks) ZDON/MMP-3 image. The original, incorrect Fig. 2 is shown below for the record. The caption to be typeset alongside it: Inhibition of TG2 attenuated the severity of surgically induced OA. (a) Representative images of safranin-O stained knee joint cartilage from sham- and DMM-operated mice (n = 8 and 10, respectively). C57BL/6 male mice at 12 week of age underwent an operation, and were intra-articularly injected with 10 μl of ZDON (200 μM) or DMSO alone as a control once a week for 7 weeks. Cartilage damage was scored by OARSI grading. (b) Representative images of immunostaining for MMP-13 in the articular cartilage. MMP-13-positive cells above the tide mark were quantified with the NIS-Elements programme (Nikon). The proportion of MMP-13-positive cells among DAPI-positive cells is displayed with dot graphs. n = 8 for sham and 10 for DMM group. The Article has been corrected.