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참돔(Pagrus major) Interleunkin 7 receptor alpha chain (IL-7Rα) 유전자의 분자유전학적 특성 및 발현분석Molecular Characterization and Expression Analysis of the Interleukin 7 Receptor Alpha Chain (IL-7Rα) Gene from Red Sea Bream (Pagrus major)
- Other Titles
- Molecular Characterization and Expression Analysis of the Interleukin 7 Receptor Alpha Chain (IL-7Rα) Gene from Red Sea Bream (Pagrus major)
- Issue Date
- 2020
- Publisher
- 한국수산해양교육학회
- Keywords
- Interleukin 7 receptor alpha chain; Red sea bream; Molecular characteristics; Tissue specific expression; Immune system
- Citation
- 수산해양교육연구, v.32, no.2, pp 560 - 569
- Pages
- 10
- Indexed
- KCI
- Journal Title
- 수산해양교육연구
- Volume
- 32
- Number
- 2
- Start Page
- 560
- End Page
- 569
- ISSN
- 1229-8999
2288-2049
- Abstract
- When a wound is infected by bacteria, macrophages recognize bacteria and release interleukin 7 receptor alpha chain (IL-7Rα). IL-7Rα released at this time activates T cells and releases IL and other similar proteins to activate various immune cells to remove bacteria. We described the molecular characteristics of PmIL-7Rα identified in red sea bream through NGS analysis and observed the tissue-specific expression of PmIL-7Rα. As a result, PmIL-7Rα showed the highest expression in the spleen among the tissues used in the experiment, and significant expression changes in the gills and kidneys after pathogen infection. We therefore believe that PmIL-7Rα plays an important role in the red sea bream's immune system.
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