A Case of Endoscopic Chemical Labyrinthectomy with Gentamicin Irrigation

Abstract

Characteristic clinical features of Meniere’s disease include vertigo, hearing loss, tinnitus, and fullness in the affected ear, and about 10% of the patients with Meniere’s disease suffer from uncontrolled vertigo attacks even after conservative therapy including diuretics. Instead of invasive treatment such as surgical labyrinthectomy, vestibulotoxic effect of gentamicin can be used for the patients with intractable Meniere’s disease. Intratympanic injection or direct application through explorative tympanotomy is widely used for application of gentamicin to the middle ear, but we report a successful case of chemical labyrinthectomy with gentamycin irrigation and direct filling-up vestibule with gentamicin through oval window via endoscopic approach.