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아메드방수유출장치삽입술 후 발생한 감염성 안내염의 임상 양상 및 예후Clinical Manifestations and Prognosis in Patients with Infectious Endophthalmitis after Ahmed Glaucoma Valve Implant Surgery

Other Titles
Clinical Manifestations and Prognosis in Patients with Infectious Endophthalmitis after Ahmed Glaucoma Valve Implant Surgery
Authors
홍채민김규남조용운김성재정인영유웅선
Issue Date
Nov-2023
Publisher
대한안과학회
Keywords
Endophthalmitis; Glaucoma drainage implant; Intravitreal injection; Vitrectomy
Citation
Journal of The Korean Ophthalmological Society, v.64, no.11, pp 1048 - 1054
Pages
7
Indexed
SCOPUS
ESCI
KCI
Journal Title
Journal of The Korean Ophthalmological Society
Volume
64
Number
11
Start Page
1048
End Page
1054
URI
https://scholarworks.gnu.ac.kr/handle/sw.gnu/68913
DOI
10.3341/jkos.2023.64.11.1048
ISSN
0378-6471
2092-9374
Abstract
목적: 아메드방수유출장치삽입술 후 발생한 감염성 안내염의 임상 양상과 치료 결과를 보고하고자 한다대상 및 방법: 2010년 1월 1일부터 2022년 5월 31일까지 아메드방수유출장치삽입술을 받은 환자의 기록을 후향적으로 검토하였고, 감염성 안내염이 발생한 환자의 임상 경과, 미생물학적 실험실 결과 및 치료에 대한 데이터를 분석하였다. 결과: 아메드방수유출장치삽입술을 받은 310안 중 9안(2.90%)에서 안내염이 발생하였다. 아메드방수유출장치삽입술과 안내염 진단사이의 평균 발생 시간 간격은 3.59년이었다. 초기 치료를 위해 모든 눈에 유리체강 내 항생제 주사를 시행하였고 4안에서 유리체절제술을 시행하였다. 삽입된 장치는 7예에서 제거되었다. 4안에서 원인균이 배양되었다. 2명의 환자는 최대교정시력이 20/200 이상이었으나 5안은 최대교정시력이 안전수동 이하였다. 결론: 아메드방수유출장치삽입술과 관련된 안내염은 드물긴 하나, 시각적 예후가 불량한 경우가 많으며 발병을 예측하기 어렵다. 따라서 아메드방수유출장치삽입술을 받는 환자는 정기적인 추적 관찰 시 교육을 받아야 하며, 수술 후 증상이 나타난 환자에 대해서는신속한 평가와 치료가 필요하다.
Purpose: We studied the clinical features and assessed the treatment outcomes of infectious endophthalmitis subsequent to Ahmed glaucoma valve (AGV) implant surgery. Methods: We performed a retrospective review of the medical records of patients who underwent AGV implant surgery between January 1, 2010 and May 31, 2022. Clinical course, microbiological lab results, and the treatment data of patients who developed infectious endophthalmitis were analyzed. Results: Of 310 eyes that underwent AGV implant surgery, 9 (2.90%) developed endophthalmitis. The average time interval between AGV implant surgery and the diagnosis of endophthalmitis was 3.59 years. As initial treatment, all affected eyes received injections of intravitreal antibiotics, while four underwent primary pars plana vitrectomy. The implanted valve was removed in seven instances. Microorganisms were found in cultures from four cases. Two patients achieved a final best-corrected visual acuity (BCVA) above 20/200, while the other five had a final BCVA of hand motion or worse. Conclusions: AGV implant-related endophthalmitis is uncommon and often results in poor visual outcomes, with unpredictable onset. Consequently, it is crucial to educate patients undergoing AGV implant surgery during regular follow-ups. Immediate evaluation and treatment are necessary for patients exhibiting symptoms after surgery. ©2023 The Korean Ophthalmological Society.
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