Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Engineering of GH11 Xylanases for Optimal pH Shifting for Industrial Applicationsopen access

Authors
Kim, In JungKim, Soo RinBornscheuer, Uwe T.Nam, Ki Hyun
Issue Date
Nov-2023
Publisher
Multidisciplinary Digital Publishing Institute (MDPI)
Keywords
engineering; GH11; pH; structure; tolerance; xylanase
Citation
Catalysts, v.13, no.11
Indexed
SCIE
SCOPUS
Journal Title
Catalysts
Volume
13
Number
11
URI
https://scholarworks.gnu.ac.kr/handle/sw.gnu/68797
DOI
10.3390/catal13111405
ISSN
2073-4344
2073-4344
Abstract
Endo-1,4-β-xylanases belonging to the glycoside hydrolase (GH) 11 family hydrolyze the β-1,4-glycosidic linkages in the xylan backbone to convert polymeric xylan into xylooligosaccharides. GH11 xylanases play an essential role in sugar metabolism and are one of the most widely used enzymes in various industries, such as pulp and paper, food and feed, biorefinery, textile, and pharmaceutical industries. pH is a crucial factor influencing the biochemical properties of GH11 xylanase and its application in bioprocessing. For the optimal pH shifting of GH11 xylanase in industrial applications, various protein engineering studies using directed evolution, rational engineering, and in silico approaches have been adopted. Here, we review the functions, structures, and engineering methods developed for the optimal pH shifting of GH11 xylanases. The various GH11 engineering techniques and key residues involved in pH shifting are discussed based on their crystal and modeled structure. This review provides an overview of recent advancements in the characterization and engineering of GH11 xylanases, providing a guide for future research in this field. © 2023 by the authors.
Files in This Item
There are no files associated with this item.
Appears in
Collections
농업생명과학대학 > 식품공학부 > Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Altmetrics

Total Views & Downloads

BROWSE