Fatal Primary Amebic Meningoencephalitis due to Naegleria fowleri: The First Imported Case in Koreaopen accessFatal Primary Amebic Meningoencephalitis due to Naegleria fowleri: The First Imported Case in Korea
- Other Titles
- Fatal Primary Amebic Meningoencephalitis due to Naegleria fowleri: The First Imported Case in Korea
- Authors
- Hong, Kyung-Wook; Jeong, Jong Hwan; Byun, Jung-Hyun; Hong, Sung-Hee; Ju, Jung-Won; Bae, In-Gyu
- Issue Date
- Oct-2023
- Publisher
- Yonsei University College of Medicine
- Keywords
- free-living ameba; Naegleria fowleri; Primary amebic meningoencephalitis
- Citation
- Yonsei Medical Journal, v.64, no.10, pp.641 - 645
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- Yonsei Medical Journal
- Volume
- 64
- Number
- 10
- Start Page
- 641
- End Page
- 645
- URI
- https://scholarworks.gnu.ac.kr/handle/sw.gnu/68054
- DOI
- 10.3349/ymj.2023.0189
- ISSN
- 0513-5796
- Abstract
- Primary amebic meningoencephalitis (PAM) is a rare, but almost always fatal, central nervous system infection caused by Naegle-ria fowleri, which are thermophilic free-living amoeba. Here, we report the first case of PAM detected in South Korea, probably imported from Thailand. Despite antimicrobial treatment for N. fowleri infection with a combination of intravenous liposomal amphotericin B, fluconazole, azithromycin, and oral rifampin, the patient died 13 days after the onset of symptoms. Clinicians in South Korea treating severe meningoencephalitis, especially in individuals returning from tropical areas, are encouraged to in-clude PAM in the differential diagnoses, given the accelerated global warming and increased overseas trips. © Yonsei University College of Medicine 2023.
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