Differential Effects of Dietary Patterns on Advanced Glycation end Products: A Randomized Crossover Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Yoona | - |
dc.contributor.author | Keogh, Jennifer B. | - |
dc.contributor.author | Deo, Permal | - |
dc.contributor.author | Clifton, Peter M. | - |
dc.date.accessioned | 2022-12-26T12:46:26Z | - |
dc.date.available | 2022-12-26T12:46:26Z | - |
dc.date.issued | 2020-06 | - |
dc.identifier.issn | 2072-6643 | - |
dc.identifier.issn | 2072-6643 | - |
dc.identifier.uri | https://scholarworks.gnu.ac.kr/handle/sw.gnu/6545 | - |
dc.description.abstract | Dietary advanced glycation end products (AGEs) are believed to contribute to pathogenesis of diabetes and cardiovascular disease. The objective of this study was to determine if a diet high in red and processed meat and refined grains (HMD) would elevate plasma concentrations of protein-bound AGEs compared with an energy-matched diet high in whole grain, dairy, nuts and legumes (HWD). We conducted a randomized crossover trial with two 4-week weight-stable dietary interventions in 51 participants without type 2 diabetes (15 men and 36 women aged 35.1 +/- 15.6 y; body mass index (BMI), 27.7 +/- 6.9 kg/m(2)). Plasma concentrations of protein-bound N epsilon-(carboxymethyl) lysine (CML), N epsilon-(1-carboxyethyl) lysine (CEL) and N delta-(5-hydro-5-methyl-4-imidazolon-2-yl)-ornithine (MG-H1) were measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The HMD significantly increased plasma concentrations (nmol/mL) of CEL (1.367, 0.78 vs. 1.096, 0.65;p< 0.01;n= 48) compared with the HWD. No differences in CML and MG-H1 between HMD and HWD were observed. HMD increased plasma CEL concentrations compared with HWD in individuals without type 2 diabetes. | - |
dc.format.extent | 11 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI | - |
dc.title | Differential Effects of Dietary Patterns on Advanced Glycation end Products: A Randomized Crossover Study | - |
dc.type | Article | - |
dc.publisher.location | 스위스 | - |
dc.identifier.doi | 10.3390/nu12061767 | - |
dc.identifier.scopusid | 2-s2.0-85086398896 | - |
dc.identifier.wosid | 000549296900001 | - |
dc.identifier.bibliographicCitation | NUTRIENTS, v.12, no.6, pp 1 - 11 | - |
dc.citation.title | NUTRIENTS | - |
dc.citation.volume | 12 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 11 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.subject.keywordPlus | INSULIN SENSITIVITY | - |
dc.subject.keywordPlus | LIPID-PEROXIDATION | - |
dc.subject.keywordPlus | OXIDATIVE STRESS | - |
dc.subject.keywordPlus | RED MEAT | - |
dc.subject.keywordPlus | INFLAMMATION | - |
dc.subject.keywordPlus | DIGESTION | - |
dc.subject.keywordPlus | PLASMA | - |
dc.subject.keywordPlus | SERUM | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | N-EPSILON-(CARBOXYMETHYL)LYSINE | - |
dc.subject.keywordAuthor | dietary advanced glycation products | - |
dc.subject.keywordAuthor | carboxymethyl-lysine (CML) | - |
dc.subject.keywordAuthor | carboxyethyl-lysine (CEL) | - |
dc.subject.keywordAuthor | methylglyoxal-hydroimidazalone (MG-H1) | - |
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