Polyhalogenation of Isoflavonoids by the Termite-Associated Actinomadura sp. RB99
- Lee, Seoung Rak; Schalk, Felix; Schwitalla, Jan W.; Benndorf, Rene; Vollmers, John; Kaster, Anne-Kristin; de Beer, Z. Wilhelm; Park, Minji; Ahn, Mi-Jeong; Jung, Won Hee; Beemelmanns, Christine; Kim, Ki Hyun
- Issue Date
- AMER CHEMICAL SOC
- JOURNAL OF NATURAL PRODUCTS, v.83, no.10, pp.3102 - 3110
- Journal Title
- JOURNAL OF NATURAL PRODUCTS
- Start Page
- End Page
- Based on high-resolution tandem mass spectrometry (HR-MS2) and global natural products social molecular networking (GNPS), we found that plant-derived daidzein and genistein derivatives are polyhalogenated by termite-associated Actinomadura species RB99. MS-guided purification from extracts of bacteria grown under optimized conditions led to the isolation of eight polychlorinated isoflavones, including six unreported derivatives, and seven novel polybrominated derivatives, two of which showed antimicrobial activity.
- Files in This Item
- There are no files associated with this item.
- Appears in
- 약학대학 > 약학과 > Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.