Etiology, Characteristics, and Outcomes of Community-Onset Pyomyositis in Korea: A Multicenter Studyopen access
- Kim, Tark; Park, Seong Yeon; Kwak, Yee Gyung; Jung, Jiwon; Kim, Min-Chul; Choi, Seong-Ho; Yu, Shi Nae; Hong, Hyo-Lim; Kim, Yong Kyun; Park, Se Yoon; Song, Eun Hee; Park, Ki-Ho; Cho, Oh Hyun; Choi, Sang-Ho
- Issue Date
- KOREAN SOC ANTIMICROBIAL THERAPY
- Pyomyositis; Community; Etiology
- INFECTION AND CHEMOTHERAPY, v.53, no.1, pp.46 - 52
- Journal Title
- INFECTION AND CHEMOTHERAPY
- Start Page
- End Page
- Background: Pyomyositis (PM) is a serious soft tissue infection and despite its clinical importance, previous studies have not been able to fully determine the clinical characteristics and microbial epidemiology of PM in Korea, which we therefore aimed to investigate. Materials and Methods: We retrospectively identified 140 adult patients diagnosed with PM from 13 general hospitals between January 2012 and December 2015. We analyzed the clinical and microbial characteristics of community-onset PM and compared them with communityacquired (CA) and healthcare-associated (HCA) PM. Results: One hundred eleven organisms were isolated from 96 (68.6%) patients with PM. Staphylococcus aureus (38 patients) was the most common pathogen, followed by streptococci (24 patients), and enteric Gram-negative organisms (27 patients). Methicillin-resistant S. aureus (MRSA) was identified in four (2.9%) patients and in-hospital mortality reached 8.6% (12/140). Enterococci isolates were identified in the HCA PM subgroup only The proportion of MRSA isolates was not comparable between CA and HCA PM subgroups. In the 83 patients with PM infected by monomicrobial pathogens, isolates of Gram-negative organisms were more commonly found in HCA PM subgroup than in CA PM subgroup (47.6% [10/21] of patients with HCA PM vs. 20.7% [12/58] of patients with CA PM; P = 0.01). Conclusion: Gram-positive cocci such as S. aureus and streptococci were dominant etiologies in community-onset PM, whereas MRSA appears to an uncommon causative organism of PM in Korea. Enteric Gram-negative organisms should also be considered as major etiologies, especially in HCA PM patient population in Korea.
- Files in This Item
- There are no files associated with this item.
- Appears in
- College of Medicine > Department of Medicine > Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.