Bipolar II disorder has the highest prevalence of seasonal affective disorder in early-onset mood disorders: Results from a prospective observational cohort study
- Yeom, Ji Won; Cho, Chul-Hyun; Jeon, Sehyun; Seo, Ju Yeon; Son, Serhim; Ahn, Yong-Min; Kim, Se Joo; Ha, Tae Hyon; Cha, Boseok; Moon, Eunsoo; Park, Dong Yeon; Baek, Ji Hyun; Kang, Hee-Ju; An, Hyonggin; Lee, Heon-Jeong
- Issue Date
- bipolar disorder; mood disorders; seasonal affective disorder; seasonal variation; young adult
- DEPRESSION AND ANXIETY, v.38, no.6, pp.661 - 670
- Journal Title
- DEPRESSION AND ANXIETY
- Start Page
- End Page
- Background Many mood disorder patients experience seasonal changes in varying degrees. Studies on seasonality have shown that bipolar disorder has a higher prevalence rate in such patients; however, there is limited research on seasonality in early-onset mood disorder patients. This study estimated the prevalence of seasonality in early-onset mood disorder patients, and examined the association between seasonality and mood disorders. Methods Early-onset mood disorder patients (n = 378; 138 major depressive disorder; 101 bipolar I disorder; 139 bipolar II disorder) of the Mood Disorder Cohort Research Consortium and healthy control subjects (n = 235) were assessed for seasonality with Seasonality Pattern Assessment Questionnaire (SPAQ). Results A higher global seasonality score, an overall seasonal impairment score, and the prevalence of seasonal affective disorder (SAD) and subsyndromal SAD showed that mood disorder subjects had higher seasonality than the healthy subjects. The former subject group had a significantly higher mean overall seasonal impairment score than the healthy subjects (p < .001); in particular, bipolar II disorder subjects had the highest prevalence of SAD, and the diagnosis of bipolar II disorder had significantly higher odds ratios for SAD when compared to major depression and bipolar I disorder (p < .05). Conclusions Early-onset mood disorders, especially bipolar II disorder, were associated with high seasonality. A thorough assessment of seasonality in early-onset mood disorders may be warranted for more personalized treatment and proactive prevention of mood episodes.
- Files in This Item
- There are no files associated with this item.
- Appears in
- College of Medicine > Department of Medicine > Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.