Redox sensor QSOX1 regulates plant immunity by targeting GSNOR to modulate ROS generationopen access
- Chae, Ho Byoung; Kim, Min Gab; Kang, Chang Ho; Park, Joung Hun; Lee, Eun Seon; Lee, Sang-Uk; Chi, Yong Hun; Paeng, Seol Ki; Bae, Su Bin; Wi, Seong Dong; Yun, Byung-Wook; Kim, Woe-Yeon; Yun, Dae-Jin; Mackey, David; Lee, Sang Yeol
- Issue Date
- CELL PRESS
- redox sensor; plant immunity; QSOX1; GSNOR; reactive oxygen species (ROS); reactive nitrogen species (RNS)
- MOLECULAR PLANT, v.14, no.8, pp.1312 - 1327
- Journal Title
- MOLECULAR PLANT
- Start Page
- End Page
- Reactive oxygen signaling regulates numerous biological processes, including stress responses in plants. Redox sensors transduce reactive oxygen signals into cellular responses. Here, we present biochemical evidence that a plant quiescin sulfhydryl oxidase homolog (QSOX1) is a redox sensor that negatively regulates plant immunity against a bacterial pathogen. The expression level of QSOX1 is inversely correlated with pathogen-induced reactive oxygen species (ROS) accumulation. Interestingly, QSOX1 both senses and regulates ROS levels by interactingn with and mediating redox regulation of S-nitrosoglutathione reductase, which, consistent with previous findings, influences reactive nitrogen-mediated regulation of ROS generation. Collectively, our data indicate that QSOX1 is a redox sensor that negatively regulates plant immunity by linking reactive oxygen and reactive nitrogen signaling to limit ROS production.
- Files in This Item
- There are no files associated with this item.
- Appears in
- 약학대학 > 약학과 > Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.