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Antibacterial effects of Mume Fructus Water Extract against Salmonella typhimurium in Murine SalmonellosisAntibacterial effects of Mume Fructus Water Extract against Salmonella typhimurium in Murine Salmonellosis
- Other Titles
- Antibacterial effects of Mume Fructus Water Extract against Salmonella typhimurium in Murine Salmonellosis
- Issue Date
- 2009
- Publisher
- 한국환경보건학회
- Keywords
- Mume Fructus water extract; antibacterial effect; salmonellosis; Salmonella typhimurium
- Citation
- 한국환경보건학회지, v.35, no.5, pp 362 - 364
- Pages
- 3
- Indexed
- KCI
- Journal Title
- 한국환경보건학회지
- Volume
- 35
- Number
- 5
- Start Page
- 362
- End Page
- 364
- ISSN
- 1738-4087
2233-8616
- Abstract
- The present study was undertaken to estimate the antibacterial effect of Mume Fructus water extract (MFWE) against murine salmonellosis. At MFWE concentrations ranging from 25 to 100 ㎍/㎖, the antibacterial effect was not showed on Salmonella typhimurium (S. typhimurium). On the other hand, bacteria without MFWE had a tendency to proliferate up to 8 h after incubation. Oral administration of MFWE at the dose of 40 ㎎/㎖ showed a therapeutic effect for S. typhimurium infected BALB/c mice. The mortality of MFWE-treated mice was 80% at 12 days, while that of MFWE-untreated mice was 100% at 9 days after a lethal dose of S. typhimurium infection. The results of our study strongly indicate that MFWE has potential as an effective of salmonellosis.
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