다발성 구진성 병변으로 나타난 무백혈성 피부 백혈병 1예

Abstract

Leukemia cutis (LC) is a cutaneous condition caused by leukemia cells leaching into the skin, with various clinical manifestations. At times, skin lesions called aleukemic LC occur before leukemia cells appear in the bone marrow or peripheral blood. Proper diagnosis of such a condition is important for early detection, treatment, and prognosis of leukemia. In general, LC is usually associated with an unfavorable prognosis. Herein, we report a case of a 65-year-old male with LC who presented with multiple papular lesions on the trunk and extremities. Histopathological examination of the lesions revealed LC of the monocytic type. Additional laboratory tests of the peripheral blood were normal, but a bone marrow biopsy demonstrated a high proportion of leukemic cells. In conclusion, we present this case to highlight that early diagnosis and accurate management are crucial for the prognosis of patients affected with leukemia, especially when skin lesions are the first clinical symptom. ? 2022 Korean Dermatological Association. All rights reserved.