Piroxicam, Mitoxantrone, and Hypofractionated Radiation Therapy with Volumetric Modulated Arc Therapy for Treating Urinary Transitional Cell Carcinoma in a Dog: A Case Reportopen accessPiroxicam, Mitoxantrone, and Hypofractionated Radiation Therapy with Volumetric Modulated Arc Therapy for Treating Urinary Transitional Cell Carcinoma in a Dog: A Case Report
- Other Titles
- Piroxicam, Mitoxantrone, and Hypofractionated Radiation Therapy with Volumetric Modulated Arc Therapy for Treating Urinary Transitional Cell Carcinoma in a Dog: A Case Report
- Authors
- 이희천
- Issue Date
- 2022
- Publisher
- 한국임상수의학회
- Keywords
- canine; palliative; radiotherapy; transitional cell carcinoma; VMAT
- Citation
- 한국임상수의학회지, v.39, no.1, pp.16 - 22
- Indexed
- SCOPUS
KCI
- Journal Title
- 한국임상수의학회지
- Volume
- 39
- Number
- 1
- Start Page
- 16
- End Page
- 22
- URI
- https://scholarworks.bwise.kr/gnu/handle/sw.gnu/2554
- DOI
- 10.17555/jvc.2022.39.1.16
- ISSN
- 1598-298X
- Abstract
- A 12-year-old spayed female beagle dog was presented with pollaki uria and stranguria. Abdominal ultrasonography identified irregular a marginat ed, hyperechoic mass in the urethra and trigon area of the bladder. Computed tomography (CT) revealed a heterogeneous mass in the trigone area leading to a urethra. There was no evidence of regional or distant metastasis. Cytologic analysis suspected transitional cell carcinoma (TCC). The patient was treated with piroxicam, mitoxantrone, and once weekly fractionated radiation therapy (RT) with volumetric modulated arc therapy (VMAT). A follow-up CT scan at 6 months after RT revealed a reduction in tumor size. At 17 months after the start of RT, the patient became severely anorectic and lethargic. Ultrasound examina tion revealed a hyperechoic mass in the apex area of bladder while the trigone area of the bladder and urethra appeared normal. Multiple hypoechoic nodules of various sizes were found in the liver and spleen. The patient was humanely euthanized at the request of the owner. A combination of piroxicam, mitoxan trone, and hypofractionated RT with VMAT protocol was well tolerated. This case described tumor response and survival time of a canine TCC treated with piroxicam, mitoxantrone, and once weekly palliative RT using computer-assisted planning and VMAT.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 수의과대학 > Department of Veterinary Medicine > Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.gnu.ac.kr/handle/sw.gnu/2554)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.