Short-term Synergistic Effect of Fruit Extracts with Red-ginseng on Forced Swimming Endurance Capacity in ICR Mice

Abstract

This study was designed to evaluate the effect of the oral administration of fruit extracts (lemon and Japanese apricot) combined with red-ginseng on the endurance and availability of metabolic substrates in ICR mice. Administration of the fruit extracts and red-ginseng (RG) (1:1) significantly increased swimming capacity, by 40%, with increased expenditures of non-esterified fatty acids and triglycerides in the plasma of the mice after I week of feeding. There was no significant increase in swimming capacity with the fruit extract alone. These results suggest that the fruit extract could synergistically elevate the effects of red-ginseng on swimming capacity in the mice by increasing fat utilization and reducing the consumption of stored glucose.