Detailed Information
Cited 10 time in 
Cited 14 time in 
Cited 14 time in
Metadata Downloads
Polyphenols Displaying Tyrosinase Inhibition from the Seed of Psoralea corylifolia
- Authors
- Kim, Jun Young; Oh, Kyeong Yeol; Kim, Ji Young; Ryu, Hyung Won; Jeong, Tae-Sook; Park, Ki Hun
- Issue Date
- Aug-2010
- Publisher
- KOREAN SOC APPLIED BIOLOGICAL CHEMISTRY
- Keywords
- monophenolase; mushroom tyrosinase; prenylated chalcone; Psoralea corylifolia
- Citation
- JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, v.53, no.4, pp 427 - 432
- Pages
- 6
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY
- Volume
- 53
- Number
- 4
- Start Page
- 427
- End Page
- 432
- ISSN
- 1738-2203
2234-344X
- Abstract
- Three chalcones and two flavanones displaying tyrosinase inhibitory activity were isolated from the seed of Psoralea corylifolia, a cultivated edible plant. The isolated compounds were elucidated. as known isovabachalcone, 4'-O-methylbavachalcone, isobavachromene, corylifolin, and bavachinin. The inhibitory potencies of the polyphenols toward monophenolase activity of mushroom tyrosinase were investigated. The inhibitory concentration (IC50) values of compounds 1-5 for monophenolase activity were determined to be 12.3, 48.8, 15.8, 23.6, and 143.91 mu M, respectively. The potent inhibitors 1-4 exhibited the competitive inhibition characteristics in analysis of Lineweaver-Burks and Dixon-plot.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - ETC > Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.