Anticoccidial efficacy of coccimuel-s composed with diclazuril on experimental and field coccidiosis in broiler chickens

Abstract

The efficacy of water soluble formulation of diclazuril (Coccimuel-S 0.5%) was tested against Eimeria spp. infection broiler chickens. The experiment was performed both experimentally infection and in the field test. CoccimuelS composed with diclazuril induced a marked inhibitory effect on the different stages of Eimeria life cycle in experimentally infected broiler chickens treated with the drug. The tested dosage levels of Coccimuel-S (0.5 ml/L, equivalent to diclazuril 2.5 ppm) in drinking water showed the significant effect compared with the control group in controlling coccidial infection and reducing the total oocyst numbers, lesion and fecal scores (p< 0.001). In addition, testing of Coccimuel-S (0.25 and 0.5 ml/L) in naturally infected poultry farms (1,200 broiler chickens), showed the significant anticoccidial effect compared to control (p< 0.001). In conclusion, addition of Coccimuel-S at the dose of 0.25 and 0.5 ml/L in the drinking water, induced efficacious effect for the treatment of coccidiosis in naturally coccidia infected broiler chickens.