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An anacardic acid analog from the jellyfish-derived fungus Paecilomyces variotii

Authors
Liu, J.Li, F.Lee, Y.M.Li, J.L.Hong, J.Yoon, W.D.Kim, E.K.Jung, J.H.
Issue Date
2012
Keywords
Anacardic acid; Antibacterial activity; Jellyfish-derived fungus; Paecilomyces variotii
Citation
Natural Product Sciences, v.18, no.1, pp 8 - 12
Pages
5
Indexed
SCOPUS
KCI
Journal Title
Natural Product Sciences
Volume
18
Number
1
Start Page
8
End Page
12
URI
https://scholarworks.gnu.ac.kr/handle/sw.gnu/23277
ISSN
1226-3907
Abstract
An anacardic acid analog (1) was isolated from the fungus Paecilomyces variotii which was derived from the giant jellyfish Nemopilema nomurai. Compound 1 was isolated from a natural source for the first time and was evaluated for antibacterial activity against human and marine pathogens, including MDR (multidrugresistant) strains. Compound 1 exhibited mild antibacterial activity against Escherichia coli DC 2, Streptococcus iniae, and methicillin-resistant Staphylococcus aureus 3089 (MRSA).
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