메토트렉세이트 중단 이후 발생한무증상-류마티스수막염Asymptomatic Rheumatoid Meningoencephalitis Presented After Discontinuation of Methotrexate
- Other Titles
- Asymptomatic Rheumatoid Meningoencephalitis Presented After Discontinuation of Methotrexate
- Authors
- 이건호; 손승남; 강희영; 박기종; 최낙천; 임병훈; 권오영; 김수경
- Issue Date
- 2014
- Publisher
- 대한신경과학회
- Keywords
- Meningoencephalitis; Rheumatoid arthritis; Methotrexate
- Citation
- 대한신경과학회지, v.32, no.1, pp 38 - 41
- Pages
- 4
- Indexed
- KCI
- Journal Title
- 대한신경과학회지
- Volume
- 32
- Number
- 1
- Start Page
- 38
- End Page
- 41
- URI
- https://scholarworks.gnu.ac.kr/handle/sw.gnu/20025
- ISSN
- 1225-7044
2299-985X
- Abstract
- Rheumatoid meningoencephalitis is a rare, but severe complication of rheumatoid arthritis (RA). A 64-year-old womanwith the history of RA presented with abnormal behaviors and memory impairments since stopping methotrexate due asymptomatic meningitis before 1 month. Brain MRI still demonstrated leptomeningeal enhancement in rightfronto-temporal area, compared with the previous. Brain biopsy revealed multiple yellowish suppurative streaks dura, and microscopically lymphoplasmic infiltrations and fibroid necrosis surrounded by granuloma. Soon afterbeginning treatment with corticosteroid and methotrexate, her symptoms improved.
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Collections - College of Medicine > Department of Medicine > Journal Articles

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