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메토트렉세이트 중단 이후 발생한무증상-류마티스수막염Asymptomatic Rheumatoid Meningoencephalitis Presented After Discontinuation of Methotrexate

Other Titles
Asymptomatic Rheumatoid Meningoencephalitis Presented After Discontinuation of Methotrexate
Authors
이건호손승남강희영박기종최낙천임병훈권오영김수경
Issue Date
2014
Publisher
대한신경과학회
Keywords
Meningoencephalitis; Rheumatoid arthritis; Methotrexate
Citation
대한신경과학회지, v.32, no.1, pp 38 - 41
Pages
4
Indexed
KCI
Journal Title
대한신경과학회지
Volume
32
Number
1
Start Page
38
End Page
41
URI
https://scholarworks.gnu.ac.kr/handle/sw.gnu/20025
ISSN
1225-7044
2299-985X
Abstract
Rheumatoid meningoencephalitis is a rare, but severe complication of rheumatoid arthritis (RA). A 64-year-old womanwith the history of RA presented with abnormal behaviors and memory impairments since stopping methotrexate due asymptomatic meningitis before 1 month. Brain MRI still demonstrated leptomeningeal enhancement in rightfronto-temporal area, compared with the previous. Brain biopsy revealed multiple yellowish suppurative streaks dura, and microscopically lymphoplasmic infiltrations and fibroid necrosis surrounded by granuloma. Soon afterbeginning treatment with corticosteroid and methotrexate, her symptoms improved.
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