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Levetiracetam을 복용하는 뇌전증 환자에서 개똥쑥에 의한 발작유발Seizure Induction by Artemisia Annua in an Epilepsy Patient Taking Levetiracetam

Other Titles
Seizure Induction by Artemisia Annua in an Epilepsy Patient Taking Levetiracetam
Authors
남원식권오영김도형김민정강혜훈정다혜정희정손승남김수경강희영박기종최낙천임병훈
Issue Date
2015
Publisher
대한신경과학회
Keywords
Artemisia annua; Seizure; Anticonvulnts
Citation
대한신경과학회지, v.33, no.1, pp 44 - 47
Pages
4
Indexed
KCI
Journal Title
대한신경과학회지
Volume
33
Number
1
Start Page
44
End Page
47
URI
https://scholarworks.gnu.ac.kr/handle/sw.gnu/18278
ISSN
1225-7044
2299-985X
Abstract
Artemisia annua is a wormwood. Because it may induce Cytochrome P450 2C19 enzyme, Artemisia annua may have an influence on antiepileptic drugs which are substrates for the enzyme. This influence may negatively affect seizure control of epilepsy patient. We present a patient whose seizures were induced by Artemisia annua, despite he was taking levetiracetam which is not a substrate for the hepatic enzyme. Therefore there would be another mechanism of seizure induction of Artemisia annua besides hepatic metabolism.
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