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Development of Advanced Macrosphelides: Potent Anticancer Agentsopen access
- Authors
- Paek, Seung-Mann
- Issue Date
- Mar-2015
- Publisher
- MDPI
- Keywords
- Analogs; Macrosphelides; Medicinal chemistry
- Citation
- MOLECULES, v.20, no.3, pp 4430 - 4449
- Pages
- 20
- Indexed
- SCIE
SCOPUS
- Journal Title
- MOLECULES
- Volume
- 20
- Number
- 3
- Start Page
- 4430
- End Page
- 4449
- ISSN
- 1420-3049
1420-3049
- Abstract
- Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography preparation. In addition, advances in their apoptosis-inducing activities are also included.
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