여성 소아 종양 완치자의 생식샘 기능

Abstract

During the last three decades childhood cancer survivorship study has extensively developed and now we have much extent of knowledge about survivor’s long-term mortality and chronic illness. One of the many challenges that females survivors face includes reproductive health, which involves reproductive and sexual health changes that could later significantly reduce one’s quality of life. Alkylating chemotherapy, irradiation of the CNS and/or ovaries, and pelvic and genitourinary surgery can adversely affect the reproductive organs. Increased awareness of the unique needs of female cancer survivors,timely evaluation of gonadal function, and active intervention for fertility preservation before, during, and after therapy is warranted.