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Synergistic antibacterial effects of a combination of cephalexin and gentamicin against Streptococci isolated from dairy cows with subclinical mastitis in Gyeongnam provinceSynergistic antibacterial effects of a combination of cephalexin and gentamicin against Streptococci isolated from dairy cows with subclinical mastitis in Gyeongnam province
- Other Titles
- Synergistic antibacterial effects of a combination of cephalexin and gentamicin against Streptococci isolated from dairy cows with subclinical mastitis in Gyeongnam province
- Issue Date
- 2017
- Publisher
- 한국예방수의학회
- Keywords
- Staphylococcus spp.; bovine mastitis; cephalexin; gentamicin; FIC index
- Citation
- 예방수의학회지, v.41, no.3, pp 124 - 128
- Pages
- 5
- Indexed
- KCI
- Journal Title
- 예방수의학회지
- Volume
- 41
- Number
- 3
- Start Page
- 124
- End Page
- 128
- ISSN
- 2287-7991
2287-8009
- Abstract
- This study investigated the synergistic effects of a combination of cephalexin and gentamicin (CCG) against Streptococcus spp. isolated from bovine milk. Minimum inhibitory concentrations (MICs) and fractional inhibitory concentration (FIC) index were determined for 12 bacteria isolated from 12 bovine farms in Gyeongnam province. The MIC ranges of cephalexin, gentamicin and CCG were 0.25-0.5, 0.5-2.0 and 0.06-0.125 μg/mL, respectively. In addition, the FIC index range of CCG against the isolates was 0.32-0.34, showing a synergistic effect in the checkboard assay. In conclusion, CCG has a high antibacterial activity against Streptococcus isolates and may be utilized in the treatment of bovine streptococcal mastitis.
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Collections - 수의과대학 > Department of Veterinary Medicine > Journal Articles
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