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Evaluation of thromboelastography analysis for treatment of heartworm disease in dogs over time: A pilot study

Authors
Han, D.Yoon, W.Lee, H.Yu, D.Jung, D.
Issue Date
Feb-2019
Publisher
Korean Society of Veterinary Clinics
Keywords
Dog; Heartworm; Hypercoagulability; Thromboelastography; Thromboembolism
Citation
Journal of Veterinary Clinics, v.36, no.1, pp 42 - 45
Pages
4
Indexed
SCOPUS
KCI
Journal Title
Journal of Veterinary Clinics
Volume
36
Number
1
Start Page
42
End Page
45
URI
https://scholarworks.gnu.ac.kr/handle/sw.gnu/10725
DOI
10.17555/jvc.2019.02.36.1.42
ISSN
1598-298X
Abstract
Thromboelastography (TEG) analysis consists of a, G, K, MA, and R types of values and tests the effectiveness of blood clotting, which can be assessed for platelet function, clotting strength, and fibrinolysis. Canine heartworm diseases caused by Dirofilaria immitis, a vascular nematode, can lead to hyperfibrinolysis and hypercoagulation. In this study, G and MA values showed a statistically significant decrease over time after treatment of heartworm disease. Additionally, the a-value showed a high correlation with G, K, MA, and R values. The G value showed a high correlation with K and MA values, while The K value showed a high correlation with MA and R values. This study clearly found a gradual decrease in G and MA values in dogs with heartworm disease over time, both before and after treatment. This suggests that the clot formation time is longer and that the intensity of clot formation is lowered and may improve the risk of thromboembolism in dogs with heartworm disease. ? 2019, Korean Society of Veterinary Clinics. All rights reserved.
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