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Clinical application of bone turnover markers in osteoporosis in Koreaopen access
- Authors
- Park, S.Y.; Ahn, S.H.; Yoo, J.-I.; Chung, Y.-J.; Jeon, Y.K.; Yoon, B.-H.; Kim, H.Y.; Lee, S.H.; Lee, J.; Hong, S.
- Issue Date
- 1-Feb-2019
- Publisher
- Korean Society for Bone and Mineral Research
- Keywords
- Biomarkers; Bone remodeling; Bone turnover markers; Chronic kidney disease; Osteoporosis
- Citation
- Journal of Bone Metabolism, v.26, no.1, pp 19 - 24
- Pages
- 6
- Indexed
- SCOPUS
KCI
- Journal Title
- Journal of Bone Metabolism
- Volume
- 26
- Number
- 1
- Start Page
- 19
- End Page
- 24
- ISSN
- 2287-6375
2287-7029
- Abstract
- Bone turnover markers (BTMs) have important role in the management of osteoporosis. Recently the clinical application of BTMs has achieved significant progress and measurement of BTMs give us better understanding of pathogenesis of osteoporosis. However, the use of BTMs is still insufficient in Korea. We summarized the available methods and standard interval of the BTMs in Korea. Also we reviewed published literatures on pre-analytical variability in the measurement of BTMs and provided recommendations for standardized sample handling and patient preparation for reducing those pre-analytical variabilities. The clinical application of BTMs in patients with chronic kidney disease who have a higher fracture risk than the general population is summarized. Copyright ? 2019 The Korean Society for Bone and Mineral Research.
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