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SCIESCOPUS
Anthocyanins from black soybean seed coats inhibit UVB-induced inflammatory cylooxygenase-2 gene expression and PGE(2) production through regulation of the nuclear factor-kappa B and phosphatidylinositol 3-kinase/Akt pathway

Tsoyi, Konstantin; Park, Hyeong Bin; Kim, Young Min; Il Chung, Jong; Shin, Sung Chul; Lee, Won Suk; Seo, Han Geuk; Lee, Jae Heun; Chang, Ki Churl; Kim, Hye Jung

ArticleIssue Date2008CitationJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, v.56, no.19, pp 8969 - 8974PublisherAMER CHEMICAL SOC
SCISCIESCOPUS
CARBON MONOXIDE FROM CORM-2 REDUCES HMGB1 RELEASE THROUGH REGULATION OF IFN-beta/JAK2/STAT-1/INOS/NO SIGNALING BUT NOT COX-2 IN TLR-ACTIVATED MACROPHAGES

Tsoyi, Konstantin; Nizamutdinova, Irina Tsoy; Jang, Hwa Jin; Mun, Lidiya; Kim, Hye Jung; Seo, Han Geuk; Lee, Jae Heun; Chang, Ki Churl

ArticleIssue Date2010CitationSHOCK, v.34, no.6, pp 608 - 614PublisherLIPPINCOTT WILLIAMS & WILKINS
SCISCIESCOPUS
CKD712, a synthetic isoquinoline alkaloid, enhances the anti-cancer effects of paclitaxel in MDA-MB-231 cells through regulation of PTEN

Kim, Young Min; Tsoyi, Konstantin; Jang, Hwa Jin; Park, Eun Jung; Park, Sang Won; Kim, Hye Jung; Hwa, Jeong Seok; Chang, Ki Churl

ArticleIssue Date2014CitationLIFE SCIENCES, v.112, no.1-2, pp 49 - 58PublisherPERGAMON-ELSEVIER SCIENCE LTD
SCISCIESCOPUS
Ethyl Pyruvate Induces Heme Oxygenase-1 Through p38 Mitogen-Activated Protein Kinase Activation by Depletion of Glutathione in RAW 264.7 Cells and Improves Survival in Septic Animalsopen access

Jang, Hwa Jin; Kim, Young Min; Tsoyi, Konstantin; Park, Eun Jung; Lee, Young Soo; Kim, Hye Jung; Lee, Jae Heun; Joe, Yeonsoo; Chung, Hun Taeg; Chang, Ki Churl

ArticleIssue Date2012CitationANTIOXIDANTS & REDOX SIGNALING, v.17, no.6, pp 878 - 889PublisherMARY ANN LIEBERT, INC
SCIESCOPUS
Heme-Oxygenase-1 Induction and Carbon Monoxide-Releasing Molecule Inhibit Lipopolysaccharide (LPS)-Induced High-Mobility Group Box 1 Release in Vitro and Improve Survival of Mice in LPS- and Cecal Ligation and Puncture-Induced Sepsis Model in Vivo

Tsoyi, Konstantin; Lee, Tae Yu; Lee, Young Soo; Kim, Hye Jung; Seo, Han Geuk; Lee, Jae Heun; Chang, Ki Churl

ArticleIssue Date2009CitationMOLECULAR PHARMACOLOGY, v.76, no.1, pp 173 - 182PublisherAMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
SCIESCOPUS
HO-1 and JAK-2/STAT-1 signals are involved in preferential inhibition of iNOS over COX-2 gene expression by newly synthesized tetrahydroisoquinoline alkaloid, CKD712, in cells activated with lipopolysacchride

Tsoyi, Konstantin; Kim, Hye Jung; Shin, Jae-Soo; Kim, Dal-Hyun; Cho, Hee-Jeong; Lee, Sung Sook; Ahn, Sun Kil; Yun-Choi, Hye Sook; Lee, Jae Heun; Seo, Han Geuk, et al.

ArticleIssue Date2008CitationCELLULAR SIGNALLING, v.20, no.10, pp 1839 - 1847PublisherELSEVIER SCIENCE INC
SCISCIESCOPUS
Metformin inhibits HMGB1 release in LPS-treated RAW 264.7 cells and increases survival rate of endotoxaemic miceopen access

Tsoyi, Konstantin; Jang, Hwa Jin; Nizamutdinova, Irina Tsoy; Kim, Young Min; Lee, Young Soo; Kim, Hye Jung; Seo, Han Geuk; Lee, Jae Heun; Chang, Ki Churl

ArticleIssue Date2011CitationBRITISH JOURNAL OF PHARMACOLOGY, v.162, no.7, pp 1498 - 1508PublisherWILEY
SCISCIESCOPUS
(+)-Nootkatone and (+)-valencene from rhizomes of Cyperus rotundus increase survival rates in septic mice due to heme oxygenase-1 induction

Tsoyi, Konstantin; Jang, Hwa Jin; Lee, Young Soo; Kim, Young Min; Kim, Hye Jung; Seo, Han Geuk; Lee, Jae Heun; Kwak, Jong Hwan; Lee, Dong-Ung; Chang, Ki Churl

ArticleIssue Date2011CitationJOURNAL OF ETHNOPHARMACOLOGY, v.137, no.3, pp 1311 - 1317PublisherELSEVIER IRELAND LTD
SCIESCOPUS
Protective Effect of Anthocyanins from Black Soybean Seed Coats on UVB-Induced Apoptotic Cell Death in Vitro and in Vivo

Tsoyi, Konstantin; Park, Hyung Bin; Kim, Young Min; Chung, Jong Il; Shin, Sung Chul; Shim, Hae Jung; Lee, Won Suk; Seo, Han Geuk; Lee, Jae Heun; Chang, Ki Churl, et al.

ArticleIssue Date2008CitationJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, v.56, no.22, pp 10600 - 10605PublisherAMER CHEMICAL SOC
SCISCIESCOPUS
PTEN differentially regulates expressions of ICAM-1 and VCAM-1 through PI3K/Akt/GSK-3 beta/GATA-6 signaling pathways in TNF-alpha-activated human endothelial cells

Tsoyi, Konstantin; Jang, Hwa Jin; Nizamutdinova, Irina Tsoy; Park, Kyungok; Kim, Young Min; Kim, Hye Jung; Seo, Han Geuk; Lee, Jae Heun; Chang, Ki Churl

ArticleIssue Date2010CitationATHEROSCLEROSIS, v.213, no.1, pp 115 - 121PublisherELSEVIER IRELAND LTD
SCIESCOPUS
Regulation of lipopolysaccharide-induced inducible nitric-oxide synthase expression through the nuclear factor-kappa B pathway and interferon-beta/tyrosine kinase 2/Janus tyrosine kinase 2-signal transducer and activator of transcription-1 signaling cascades by 2-naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (THI 53), a new synthetic isoquinoline alkaloid

Kim, Hye Jung; Tsoyi, Konstantin; Heo, Ja Myung; Kang, Young Jin; Park, Min Kyu; Lee, Young Soo; Lee, Jae Heun; Seo, Han Geuk; Yun-Choi, Hye Sook; Chang, Ki Churl

ArticleIssue Date2007CitationJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, v.320, no.2, pp 782 - 789PublisherAMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
SCISCIESCOPUS
(S)-1-alpha-naphthylmethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD712), promotes wound closure by producing VEGF through HO-1 induction in human dermal fibroblasts and mouse skinopen access

Jang, Hwa Jin; Tsoyi, Konstantin; Kim, Young Min; Park, Eun Jung; Park, Sang Won; Kim, Hye Jung; Lee, Jae Heun; Chang, Ki Churl

ArticleIssue Date2013CitationBRITISH JOURNAL OF PHARMACOLOGY, v.168, no.6, pp 1485 - 1496PublisherWILEY-BLACKWELL
SCISCIESCOPUS
Stimulation of Alpha7 Nicotinic Acetylcholine Receptor by Nicotine Attenuates Inflammatory Response in Macrophages and Improves Survival in Experimental Model of Sepsis Through Heme Oxygenase-1 Induction

Tsoyi, Konstantin; Jang, Hwa Jin; Kim, Jong Woo; Chang, Hong Kyung; Lee, Young Soo; Pae, Hyun-Ock; Kim, Hye Jung; Seo, Han Geuk; Lee, Jae Heun; Chung, Hun-Taeg, et al.

ArticleIssue Date2011CitationANTIOXIDANTS & REDOX SIGNALING, v.14, no.11, pp 2057 - 2070PublisherMARY ANN LIEBERT, INC
SCIESCOPUS
The Heme Oxygenase-1 Inducer THI-56 Negatively Regulates iNOS Expression and HMGB1 Release in LPS-Activated RAW 264.7 Cells and CLP-Induced Septic Miceopen access

Park, Eun Jung; Jang, Hwa Jin; Tsoyi, Konstantin; Kim, Young Min; Park, Sang Won; Kim, Hye Jung; Lee, Jae Heun; Chang, Ki Churl

ArticleIssue Date2013CitationPLOS ONE, v.8, no.10PublisherPUBLIC LIBRARY SCIENCE
SCIESCOPUS
Upregulation of PTEN by CKD712, a synthetic tetrahydroisoquinoline alkaloid, selectively inhibits lipopolysaccharide-induced VCAM-1 but not ICAM-1 expression in human endothelial cells

Tsoyi, Konstantin; Kim, Woo Sang; Kim, Young Min; Kim, Hye Jung; Seo, Han Geuk; Lee, Jae Heun; Yun-Choi, Hye Sook; Chang, Ki Churl

ArticleIssue Date2009CitationATHEROSCLEROSIS, v.207, no.2, pp 412 - 419PublisherELSEVIER IRELAND LTD
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