Data on molecular characterization and expression profiles of the NF-κB repressing factor gene in red sea bream (Pagrus major)

Choi, K.-M.; Hwang, J.Y.; Kwon, M.-G.; Jeong, J.-M.; Seo, J.S.; Hwang, S.D.; Jee, B.-Y.; Kim, M.-C.; Park, C.-I.

doi:10.1016/j.dib.2019.103977

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Data on molecular characterization and expression profiles of the NF-κB repressing factor gene in red sea bream (Pagrus major)

Choi, K.-M.;
Hwang, J.Y.;
Kwon, M.-G.;
Jeong, J.-M.;
Seo, J.S.;
... Kim, M.-C.;
... Park, C.-I.;
외 2명

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초록

Nuclear factor-kappaB (NF-κB) repressing factor (NKRF) specifically inhibits the transcriptional activity of NF-κB protein. The PmNKRF cDNA is composed of 757 amino acid residues. Alignment analysis revealed that the G-patch and R3H domains are conserved in different organisms. We aimed to analyse red sea bream NKRF (PmNKRF) gene expression after infection with pathogens [Streptococcus iniae or red sea bream iridovirus (RSIV)] and in healthy individuals. In healthy individuals, PmNKRF was ubiquitously expressed in all 12 tested tissues, predominantly in the head kidney and spleen. Expression of PmNKRF was significantly up-regulated in the gills, kidney, liver and spleen after RSIV infection. After S. iniae infection, PmNKRF expression was significantly down-regulated in the gills and significantly up-regulated in the kidney, liver and spleen. ? 2019 The Author(s)

키워드

NF-κB repressing factor; Pagrus major; Red sea bream iridovirus; Streptococcus iniae

제목: Data on molecular characterization and expression profiles of the NF-κB repressing factor gene in red sea bream (Pagrus major)

저자: Choi, K.-M.; Hwang, J.Y.; Kwon, M.-G.; Jeong, J.-M.; Seo, J.S.; Hwang, S.D.; Jee, B.-Y.; Kim, M.-C.; Park, C.-I.

DOI: 10.1016/j.dib.2019.103977

발행일: 2019-06

유형: Data Paper

저널명: Data in Brief

권: 24

언어: ENG

출판사: Elsevier Inc.

발행국가: 네덜란드

ISSN: P 2352-3409