Extreme thrombocytosis associated with transient myeloproliferative disorder with Down syndrome with t(11;17)(q13;q21)

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초록

A female patient with Down Syndrome (DS) had neonatal thrombocytosis with platelet counts exceeding 2,000 x 10(3)/mu L and transient myeloproliferative disorder (TMD). Platelet counts remained elevated the first 2 months of life. A translocation located between chromosomes 17 and 11 was observed. We describe a patient with thrombocytosis and TMD showing ail 11q13 translocation. The leukocytosis and thrombocytosis improved after an exchange transfusion.

키워드

excessive thrombocytosistransient myeloproliferative disorderLEUKEMIA
제목
Extreme thrombocytosis associated with transient myeloproliferative disorder with Down syndrome with t(11;17)(q13;q21)
저자
Park, Eun-SilKim, So-YoungYeom, Jung-SukLim, Jae-YoungPark, Chan-HooYoun, Hee-Shang
DOI
10.1002/pbc.21029
발행일
2008-03
유형
Article
저널명
Pediatric Blood and Cancer
50
3
페이지
643 ~ 644