Copper(II)-Catalyzed N-Arylationand N-Vinylation of Oxadiazolones with BoronicAcids under Mild Conditions

  • Park, Yeongmi; 
  • Kim, Minsuk; 
  • Yun, Hyobin; 
  • Chung, SeungWon; 
  • Kim, Jungwon; 
  • 외 1명
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초록

An efficient copper-catalyzed method for forming C-N bonds between oxadiazolones and boronic acids has been developed. Readily accessible aryl and vinylboronic acids serve as the coupling partners under mild conditions, enabling a wide substrate scope. This approach affords a variety of N-arylated and N-vinylated oxadiazolones under mild reaction conditions in a practical and cost-effective manner.

키워드

ARYLBORONIC ACID; DERIVATIVES; BIOISOSTERES; DESIGN
제목
Copper(II)-Catalyzed N-Arylationand N-Vinylation of Oxadiazolones with BoronicAcids under Mild Conditions
저자
Park, Yeongmi; Kim, Minsuk; Yun, Hyobin; Chung, SeungWon; Kim, Jungwon; Son, Jongwoo
DOI
10.1021/acs.joc.6c00689
발행일
2026-07
유형
Article; Early Access
저널명
The Journal of Organic Chemistry
권
91
호
31
페이지
10637 ~ 10642