BODIPY-functionalized gold nanoparticles as a selective fluoro-chromogenic chemosensor for imaging Cu2+ in living cells

Lee, Hye Young; Son, Hyunjong; Lim, Jung Mi; Oh, Jungmin; Kang, Dongmin; Han, Won Seok; Jung, Jong Hwa

doi:10.1039/c0an00129e

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BODIPY-functionalized gold nanoparticles as a selective fluoro-chromogenic chemosensor for imaging Cu2+ in living cells

Lee, Hye Young;
Son, Hyunjong;
Lim, Jung Mi;
Oh, Jungmin;
Kang, Dongmin;
... Jung, Jong Hwa;
외 1명

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초록

A new fluoro-chromogenic chemosensor based on BODIPY-functionalized gold nanoparticles 1 is prepared. Addition of Cu2+ ions to aqueous solutions of 1 gave an instantaneous color change along with a blue-shift of the absorption band and quenching of the emission spectrum at room temperature. The chemosensor 1 exhibits a high affinity and selectivity for Cu2+ over competing metal ions tested. Moreover, confocal microscopy experiments establish that 1 can be used for detecting Cu2+ levels within living cells.

키워드

INORGANIC HYBRID MATERIALS; ON FLUORESCENT SENSOR; COPPER(II) ION; SILICA; CU(II)

제목: BODIPY-functionalized gold nanoparticles as a selective fluoro-chromogenic chemosensor for imaging Cu2+ in living cells

저자: Lee, Hye Young; Son, Hyunjong; Lim, Jung Mi; Oh, Jungmin; Kang, Dongmin; Han, Won Seok; Jung, Jong Hwa

DOI: 10.1039/c0an00129e

발행일: 2010

유형: Article

저널명: The Analyst

권: 135

호: 8

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