BODIPY-functionalized gold nanoparticles as a selective fluoro-chromogenic chemosensor for imaging Cu2+ in living cells

  • Lee, Hye Young; 
  • Son, Hyunjong; 
  • Lim, Jung Mi; 
  • Oh, Jungmin; 
  • Kang, Dongmin; 
  • ... Jung, Jong Hwa; 
  • 외 1명
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초록

A new fluoro-chromogenic chemosensor based on BODIPY-functionalized gold nanoparticles 1 is prepared. Addition of Cu2+ ions to aqueous solutions of 1 gave an instantaneous color change along with a blue-shift of the absorption band and quenching of the emission spectrum at room temperature. The chemosensor 1 exhibits a high affinity and selectivity for Cu2+ over competing metal ions tested. Moreover, confocal microscopy experiments establish that 1 can be used for detecting Cu2+ levels within living cells.

키워드

INORGANIC HYBRID MATERIALS; ON FLUORESCENT SENSOR; COPPER(II) ION; SILICA; CU(II)
제목
BODIPY-functionalized gold nanoparticles as a selective fluoro-chromogenic chemosensor for imaging Cu2+ in living cells
저자
Lee, Hye Young; Son, Hyunjong; Lim, Jung Mi; Oh, Jungmin; Kang, Dongmin; Han, Won Seok; Jung, Jong Hwa
DOI
10.1039/c0an00129e
발행일
2010
유형
Article
저널명
Analyst
권
135
호
8
페이지
2022 ~ 2027