A new cytotoxic guaianolide from Chrysanthemum boreale

Park, Ki Hun; Yang, Min Suk; Park, Moon Ki; Kim, Sang Chan; Yang, Chae Ha; Park, Sook Jahr; Lee, Jong Rok

doi:10.1016/j.fitote.2008.09.013

상세 보기

A new cytotoxic guaianolide from Chrysanthemum boreale

Park, Ki Hun;
Yang, Min Suk;
Park, Moon Ki;
Kim, Sang Chan;
Yang, Chae Ha;
외 2명

Citations

WEB OF SCIENCE

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초록

A new cytotoxic guaianolide was isolated from Chrysanthemum boreale Makino. The structure of guaianolide was elucidated as 8-acetoxy-4,10-dihydroxy-2,11(13)-guaiadiene-12,6-olide (1). Compound I exhibited cytotoxic activity (IC(50 <=)4 mu g/ml) against all five human cancer cell lines tested. (C) 2008 Elsevier B.V. All rights reserved.

키워드

Chrysanthemum boreale Makino; Guaianolide; 8-acetoxy-4,10-dihydroxy-2,11(13)-guaiadiene-12,6-olide; Cytotoxic activity

제목: A new cytotoxic guaianolide from Chrysanthemum boreale

저자: Park, Ki Hun; Yang, Min Suk; Park, Moon Ki; Kim, Sang Chan; Yang, Chae Ha; Park, Sook Jahr; Lee, Jong Rok

DOI: 10.1016/j.fitote.2008.09.013

발행일: 2009-01

유형: Article

저널명: Fitoterapia

권: 80

호: 1

페이지: 54 ~ 56

언어: ENG

출판사: ELSEVIER

발행국가: 네덜란드

분량: 3 페이지

ISSN: E 1873-6971
P 0367-326X