Explainable AI based feature selection in cancer RNA-seq
Citations

WEB OF SCIENCE

0
Citations

SCOPUS

1

초록

Identifying informative features in bioinformatics is challenging due to their small proportion within large datasets. We propose a scalable and interpretable feature selection framework for cancer RNA-seq by transforming non-image bio-data into 2D formats and applying convolutional neural networks (CNNs) with transfer learning for efficient classification. Explainable artificial intelligence (XAI) techniques identify and prioritize important features, while principal component analysis (PCA) determines the optimal number of selected features, ensuring transparency and reliability. Comparative analysis of CNN and XAI highlights the effectiveness of our approach, providing a robust framework for high-dimensional genomic data analysis with applications in cancer diagnosis and prognosis. © 2025

키워드

CNNFeature selectionRNA-seqTransfer learningXAI
제목
Explainable AI based feature selection in cancer RNA-seq
저자
Seo, HyeinPark, Jae-HoLee, JanghoChung, Byung Chang
DOI
10.1016/j.icte.2025.05.004
발행일
2025-08
유형
Article
저널명
ICT Express
11
4
페이지
603 ~ 610