해면골 비율이 저강도 집속 초음파에 미치는 영향 분석: 시뮬레이션 연구

초록

Transcranial Focused Ultrasound(tFUS) is a technique that concentrates energy on specific regions of the brain to modulate neural activity. The accurate prediction is difficult due to the skull, so medical imaging simulations are used. In particular, the presence of cancellous bone located in the middle of the skull has been reported as a significant factor, but its impact has not been systematically analyzed. So, we modeled the skull as a simple sphere to focus on the effect of cancellous bone while excluding other factors and analyzed the results by varying the cancellous bone ratio. As a result, maximum pressure decreased and increased again as the cancellous bone increased, and focusing area decreased overall. It is expected that future studies will be able to develop an AI model that predicts induced sound pressure according to the cancellous bone ratio and provide personalized results.

키워드