Design of DNA Storage Coding Scheme with LDPC Codes and Interleaving
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초록

In this paper, we propose a new coding scheme for DNA storage using low-density parity-check (LDPC) codes and interleaving techniques. While conventional coding schemes generally employ error correcting codes in both inter and intra-oligo directions, we show that inter-oligo LDPC codes, optimized by differential evolution, are sufficient in ensuring the reliability of DNA storage due to the powerful <italic>soft decoding of LDPC codes</italic>. In addition, we apply <italic>interleaving techniques</italic> for handling non-uniform error characteristics of DNA storage to enhance the decoding performance. Consequently, the proposed coding scheme reduces the required number of oligo reads for perfect recovery by 26.25% ~ 38.5% compared to existing state-of-the-art coding schemes. Moreover, we develop an analytical DNA channel model in terms of non-uniform binary symmetric channels. This mathematical model allows us to demonstrate the superiority of the proposed coding scheme while isolating the experimental variation, as well as confirm the independent effects of LDPC codes and interleaving techniques. IEEE

키워드

CodesDecodingDNADNA storageEncodingError correction codesinter-oligo codinginterleavinglow-density parity-check (LDPC) codenon-uniformityParity check codesSequential analysisAPPROACHING CONSTRAINED CODESDIGITAL INFORMATIONCAPACITYSEQUENCESROBUST
제목
Design of DNA Storage Coding Scheme with LDPC Codes and Interleaving
저자
Kim, Jae-WonJeong, JaehoKwak, Hee-YoulNo, Jong-Seon
DOI
10.1109/TNB.2024.3379976
발행일
2024-07
유형
Article
저널명
IEEE Transactions on Nanobioscience
23
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