CD3+/CD4+/CD5+/CD8+/CD21+/CD34-/ CD45-/CD79a-/TCRαβ+/TCRγδ-/MHCII+ T-zone lymphoma in a dog with generalized lymphadenopathy: A case report

CD3+/CD4+/CD5+/CD8+/CD21+/CD34-/CD45-/CD79a-/TCRαβ+/TCRγδ-/MHCII+ T-zone lymphoma in a dog with generalized lymphadenopathy: a case report
Citations

SCOPUS

6

초록

Canine T-zone lymphoma (TZL) is a mature T-cell lymphoma in dogs. The diagnosis and sub-classification are impossible without biopsy or immunophenotyping by flow cytometry. An 11-year-old, spayed, female Golden Retriever presented with lymph node enlargement. Clinical examination was consistent with canine multicentric lymphoma. However, immunophenotyping revealed positive for CD3, CD4, CD5, CD8, CD21, TCRαβ, and MHCII but negative for CD34, CD45, CD79a, and TCRγδ. Histopathology revealed lymphocytes expanding to the cortex-preserving architecture and thinning of the nodal capsule, and CD3 positive but PAX-5 negative. Owing to the indolent nature of TZL, careful monitoring approach without clinical intervention was utilized. ? 2021 The Korean Society of Veterinary Science.

키워드

Case reportDogFlow cytometryImmunophenotypingLymphoma
제목
CD3+/CD4+/CD5+/CD8+/CD21+/CD34-/ CD45-/CD79a-/TCRαβ+/TCRγδ-/MHCII+ T-zone lymphoma in a dog with generalized lymphadenopathy: A case report
제목 (타언어)
CD3+/CD4+/CD5+/CD8+/CD21+/CD34-/CD45-/CD79a-/TCRαβ+/TCRγδ-/MHCII+ T-zone lymphoma in a dog with generalized lymphadenopathy: a case report
저자
Shin, S.W.Lim, Y.J.Bae, H.Kim, J.Cho, A.Park, J.Lee, D.Jung, D.-I.Kim, S.-K.Yu, D.
DOI
10.14405/kjvr.2021.61.e21
발행일
2021
유형
Article
저널명
대한수의학회지
61
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