Embryonal rhabdomyosarcoma in a Siberian chipmunk (Tamias sibiricus): a case report

  • Kong, J. Y.; 
  • Kim, H. K.; 
  • Lee, H. J.; 
  • Yeon, S. C.; 
  • Park, J. K.; 
  • ... Hong, I. H.; 
  • 외 1명
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초록

A 2-year-old female Siberian chipmunk (Tamias sibiricus) was presented to the veterinary clinic for swelling, pain and lameness of the left rear leg. Radiologically, an invasive tumour around the distal femur was suspected, and the leg was surgically amputated and submitted for histopathological diagnosis. Microscopically, the mass was densely packed with multinucleated strap cells that had round-to-oval, or elongated nuclei with prominent nucleoli. These neoplastic cells occasionally formed myotubes with cross-striations and were immunohistochemically positive for muscle markers including desmin and myogenin. Consequently, embryonal rhabdomyosaroma myotubular variant of the leg with metastasis to the femur was diagnosed. Spontaneous rhabdomyosaromas are rare tumours in animals and humans, and this is the first report of its occurrence in a Siberian chipmunk.

키워드

myogenin; PTAH stain; rodents; skeletal muscle; squirrel; SPRAGUE-DAWLEY RAT; CELL CARCINOMA; GRAY SQUIRREL; ADENOCARCINOMA; LYMPHOMA; TUMOR; MICE
제목
Embryonal rhabdomyosarcoma in a Siberian chipmunk (Tamias sibiricus): a case report
저자
Kong, J. Y.; Kim, H. K.; Lee, H. J.; Yeon, S. C.; Park, J. K.; Jeong, K. S.; Hong, I. H.
DOI
10.17221/173/2016-VETMED
발행일
2017
유형
Article
저널명
Veterinarni Medicina
권
62
호
9
페이지
527 ~ 531