Pembrolizumab for Refractory Metastatic Myxofibrosarcoma: A Case Report

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초록

Myxofibrosarcoma is a rare tumor, refractory to cytotoxic chemotherapy and radiotherapy. Pembrolizumab is an innovative immunotherapy drug consisting of programmed death receptor ligand 1 antibody proven to be useful for numerous types of cancer cells. A patient had been diagnosed with metastatic myxofibrosarcoma, refractory to radiotherapy and conventional cytotoxic chemotherapy. The patient achieved a partial response during palliative chemotherapy with pembrolizumab for 14 cycles. To the best of our knowledge, this is the first case report demonstrating the efficacy of pembrolizumab for refractory myxofibrosarcoma.

키워드

Sarcoma; Immunotherapy; Pembrolizumab; PHASE-2 TRIAL; OPEN-LABEL; RECURRENCE; CARCINOMA; THERAPY; CANCER
제목
Pembrolizumab for Refractory Metastatic Myxofibrosarcoma: A Case Report
저자
Song, Haa-Na; Kang, Min Gyu; Park, Jeong Rang; Hwang, Jin-Yong; Kang, Jung Hun; Lee, Won Seop; Lee, Gyeong-Won
DOI
10.4143/crt.2017.529
발행일
2018-10
유형
Article
저널명
Cancer Research and Treatment
권
50
호
4
페이지
1458 ~ 1461