상세 보기
- Jang, Min-Jeong;
- Cho, Hye Jeong;
- Park, Young-Soo;
- Lee, Hye-Young;
- Bae, Eun-Kyung;
- 외 21명
WEB OF SCIENCE
11SCOPUS
11초록
Haplotype-level allelic characterization facilitates research on the functional, evolutionary and breeding-related features of extremely large and complex plant genomes. We report a 21.7-Gb chromosome-level haplotype-resolved assembly in Pinus densiflora. We found genome rearrangements involving translocations and inversions between chromosomes 1 and 3 of Pinus species and a proliferation of specific long terminal repeat (LTR) retrotransposons (LTR-RTs) in P. densiflora. Evolutionary analyses illustrated that tandem and LTR-RT-mediated duplications led to an increment of transcription factor (TF) genes in P. densiflora. The haplotype sequence comparison showed allelic imbalances, including presence-absence variations of genes (PAV genes) and their functional contributions to flowering and abiotic stress-related traits in P. densiflora. Allele-aware resequencing analysis revealed PAV gene diversity across P. densiflora accessions. Our study provides insights into key mechanisms underlying the evolution of genome structure, LTR-RTs and TFs within the Pinus lineage as well as allelic imbalances and diversity across P. densiflora.
키워드
- 제목
- Haplotype-resolved genome assembly and resequencing analysis provide insights into genome evolution and allelic imbalance in <i>Pinus densiflora</i>
- 저자
- Jang, Min-Jeong; Cho, Hye Jeong; Park, Young-Soo; Lee, Hye-Young; Bae, Eun-Kyung; Jung, Seungmee; Jin, Hongshi; Woo, Jongchan; Park, Eunsook; Kim, Seo-Jin; Choi, Jin-Wook; Chae, Geun Young; Guk, Ji-Yoon; Kim, Do Yeon; Kim, Sun-Hyung; Kang, Min-Jeong; Lee, Hyoshin; Cheon, Kyeong-Seong; Kim, In Sik; Kim, Yong-Min; Kim, Myung-Shin; Ko, Jae-Heung; Kang, Kyu-Suk; Choi, Doil; Park, Eung-Jun; Kim, Seungill
- 발행일
- 2024-11
- 유형
- Article
- 저널명
- Nature Genetics
- 권
- 56
- 호
- 11
- 페이지
- 2551 ~ 2561