Benefits of Soybean in the Era of Precision Medicine: A Review of Clinical Evidence
Benefits of Soybean in the Era of Precision Medicine: A Review of Clinical Evidence
Citations

WEB OF SCIENCE

5
Citations

SCOPUS

6

초록

Soybean (Glycine max) is an important ingredient of cuisines worldwide. While there is a wealth of evidence that soybean could be a good source of macronutrients and phytochemicals with healthpromoting effects, concerns regarding adverse effects have been raised. In this work, we reviewed the current clinical evidence focusing on the benefits and risks of soybean ingredients. In breast, prostate, colorectal, ovarian, and lung cancer, epidemiological studies showed an inverse association between soybean food intake and cancer risks. Soybean intake was inversely correlated with risks of type 2 diabetes mellitus (T2DM), and soy isoflavones ameliorated osteoporosis and hot flashes. Notably, soybean was one of the dietary protein sources that may reduce the risk of breast cancer and T2DM. However, soybean had adverse effects on certain types of drug treatment and caused allergies. In sum, this work provides useful considerations for planning clinical soybean research and selecting dietary protein sources for human health.

키워드

Soybeansoy isoflavonemeta-analysisprecision medicineBREAST-CANCER RISKSOY FOOD-CONSUMPTIONESTROGEN-RECEPTOR-ALPHADIETARY PHYTOESTROGENSPOSTMENOPAUSAL WOMENANTIOXIDANT ACTIVITYDIABETES-MELLITUSKOREAN POPULATIONISOFLAVONE INTAKECROSS-REACTIVITY
제목
Benefits of Soybean in the Era of Precision Medicine: A Review of Clinical Evidence
제목 (타언어)
Benefits of Soybean in the Era of Precision Medicine: A Review of Clinical Evidence
저자
Kang Jung HyunDong ZigangShin Seung Ho
DOI
10.4014/jmb.2308.08016
발행일
2023-12
유형
Review
저널명
Journal of Microbiology and Biotechnology
33
12
페이지
1552 ~ 1562