Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool -Amino Acids for Natural Product Synthesis

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초록

Chiral pool -amino acids have been used as powerful tools for the total synthesis of structurally diverse natural products. Some common naturally occurring -amino acids are readily available in both enantiomerically pure forms. The applications of the chiral pool in asymmetric synthesis can be categorized prudently as chiral sources, devices, and inducers. This review specifically examines recent advances in substrate-controlled asymmetric reactions induced by the chirality of -amino acid templates in natural product synthesis research and related areas.

키워드

chiral pool; alpha-amino acid; natural product; total synthesis; asymmetric induction; LEGIONAMINIC ACID; ALKALOIDS; METABOLITES; CYCLOADDITION; INDOLIZIDINES; CATALYSIS; ETHERS; FUNGUS; OXIDES
제목
Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool -Amino Acids for Natural Product Synthesis
저자
Paek, Seung-Mann; Jeong, Myeonggyo; Jo, Jeyun; Heo, Yu Mi; Han, Young Taek; Yun, Hwayoung
DOI
10.3390/molecules21070951
발행일
2016-07
유형
Review
저널명
Molecules
권
21
호
7