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참돔(Pagrus major) Interleunkin 7 receptor alpha chain (IL-7Rα) 유전자의 분자유전학적 특성 및 발현분석
Molecular Characterization and Expression Analysis of the Interleukin 7 Receptor Alpha Chain (IL-7Rα) Gene from Red Sea Bream (Pagrus major)
- 손민영;
- 최광민;
- 주민수;
- 박찬일
초록
When a wound is infected by bacteria, macrophages recognize bacteria and release interleukin 7 receptor alpha chain (IL-7Rα). IL-7Rα released at this time activates T cells and releases IL and other similar proteins to activate various immune cells to remove bacteria. We described the molecular characteristics of PmIL-7Rα identified in red sea bream through NGS analysis and observed the tissue-specific expression of PmIL-7Rα. As a result, PmIL-7Rα showed the highest expression in the spleen among the tissues used in the experiment, and significant expression changes in the gills and kidneys after pathogen infection. We therefore believe that PmIL-7Rα plays an important role in the red sea bream's immune system.
키워드
Interleukin 7 receptor alpha chain; Red sea bream; Molecular characteristics; Tissue specific expression; Immune system
- 제목
- 참돔(Pagrus major) Interleunkin 7 receptor alpha chain (IL-7Rα) 유전자의 분자유전학적 특성 및 발현분석
- 제목 (타언어)
- Molecular Characterization and Expression Analysis of the Interleukin 7 Receptor Alpha Chain (IL-7Rα) Gene from Red Sea Bream (Pagrus major)
- 저자
- 손민영; 최광민; 주민수; 박찬일
- 발행일
- 2020
- 저널명
- 수산해양교육연구
- 권
- 32
- 호
- 2
- 페이지
- 560 ~ 569
- 언어
- KOR
- 출판사
- 한국수산해양교육학회
- 발행국가
- 대한민국
- 분량
- 10 페이지
- ISSN
- E 2288-2049
P 1229-8999